Activation of neuronal regeneration signal following neuronal degeneration^|^mdash;involvement of microglia
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چکیده
منابع مشابه
Review Paper: Polyphenolic Antioxidants and Neuronal Regeneration
Many studies indicate that oxidative stress is involved in the pathophysiology of neurodegenerative diseases. Oxidative stress can induce neuronal damages, modulate intracellular signaling and ultimately leads to neuronal death by apoptosis or necrosis. To review antioxidants preventive effects on oxidative stress and neurodegenerative diseases we accumulated data from internatio...
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BACKGROUND Oxidative stress is known to play an important role in the pathology of traumatic brain injury. Mitochondria are thought to be the major source of the damaging reactive oxygen species (ROS) following TBI. However, recent work has revealed that the membrane, via the enzyme NADPH oxidase can also generate the superoxide radical (O(2)(-)), and thereby potentially contribute to the oxida...
متن کاملMicroglia in Neuronal Circuits
1 Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854, USA 2Children’s Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA 3Department of Neurobiology, Zhejiang University School of Medicine, 866 Yu Hang Tang Road, Hangzhou, Zhejiang 310058, China 4Department of Psychiatry, University of British Columbia, 2211 Wesbrook Mall, Vanc...
متن کاملreview paper: polyphenolic antioxidants and neuronal regeneration
many studies indicate that oxidative stress is involved in the pathophysiology of neurodegenerative diseases. oxidative stress can induce neuronal damages, modulate intracellular signaling and ultimately leads to neuronal death by apoptosis or necrosis. to review antioxidants preventive effects on oxidative stress and neurodegenerative diseases we accumulated data from international medical jou...
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Introduction: Psychomotor performance task is used to assess the arousal and cognitive functions of the central nervous system. Alternatively, human visual working memory reflects the capability of the individual’s short-term memory. Psycho-mental stimuli are linked to the stimulation of Malondialdehyde (MDA) formations. Citicoline is a nootropic nucleotide agent with a favorable effect on the ...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 2013
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.142.17